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Matrix Metalloproteinase 8 (Collagenase 2) Induces the Expression of Interleukins 6 and 8 in Breast Cancer Cells

Matrix metalloproteinase 8 (MMP-8) is a tumor-suppressive protease that cleaves numerous substrates, including matrix proteins and chemokines. In particular, MMP-8 proteolytically activates IL-8 and, thereby, regulates neutrophil chemotaxis in vivo. We explored the effects of expression of either a...

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Detalles Bibliográficos
Autores principales:	Thirkettle, Sally, Decock, Julie, Arnold, Hugh, Pennington, Caroline J., Jaworski, Diane M., Edwards, Dylan R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675567/ https://www.ncbi.nlm.nih.gov/pubmed/23632023 http://dx.doi.org/10.1074/jbc.M113.464230

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