Cargando…

Sphingolipid Domains in the Plasma Membranes of Fibroblasts Are Not Enriched with Cholesterol

The plasma membranes of mammalian cells are widely expected to contain domains that are enriched with cholesterol and sphingolipids. In this work, we have used high-resolution secondary ion mass spectrometry to directly map the distributions of isotope-labeled cholesterol and sphingolipids in the pl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frisz, Jessica F., Klitzing, Haley A., Lou, Kaiyan, Hutcheon, Ian D., Weber, Peter K., Zimmerberg, Joshua, Kraft, Mary L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2013
Materias:	Lipids
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675618/ https://www.ncbi.nlm.nih.gov/pubmed/23609440 http://dx.doi.org/10.1074/jbc.M113.473207

Ejemplares similares

Regulation of Sphingolipid Biosynthesis by the Morphogenesis Checkpoint Kinase Swe1
por: Chauhan, Neha, et al.
Publicado: (2016)

National trends in total cholesterol obscure heterogeneous changes in HDL and non-HDL cholesterol and total-to-HDL cholesterol ratio: a pooled analysis of 458 population-based studies in Asian and Western countries
Publicado: (2020)

Kdo(2)-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy
por: Sims, Kacee, et al.
Publicado: (2010)

Prion Infection Impairs Cholesterol Metabolism in Neuronal Cells
por: Cui, Huanhuan L., et al.
Publicado: (2014)

Achievement of low-density lipoprotein cholesterol goals in 18 countries outside Western Europe: The International ChoLesterol management Practice Study (ICLPS)
por: Danchin, Nicolas, et al.
Publicado: (2018)

Effects of a Disrupted Blood-Brain Barrier on Cholesterol Homeostasis in the Brain
por: Saeed, Ahmed A., et al.
Publicado: (2014)

The Endoplasmic Reticulum Coat Protein II Transport Machinery Coordinates Cellular Lipid Secretion and Cholesterol Biosynthesis
por: Fryer, Lee G. D., et al.
Publicado: (2014)

Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase Cζ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP(2))
por: Nomikos, Michail, et al.
Publicado: (2015)

Cholesterol-lowering effects of oat β-glucan: a meta-analysis of randomized controlled trials(1)(2)(3)(4)
por: Whitehead, Anne, et al.
Publicado: (2014)

Randomized controlled study of the effect of a butter naturally enriched in trans fatty acids on blood lipids in healthy women(1)(2)(3)
por: Lacroix, Émilie, et al.
Publicado: (2012)

The phospholipase PNPLA7 functions as a lysophosphatidylcholine hydrolase and interacts with lipid droplets through its catalytic domain
por: Heier, Christoph, et al.
Publicado: (2017)

Lipid Raft Association and Cholesterol Sensitivity of P2X1-4 Receptors for ATP: CHIMERAS AND POINT MUTANTS IDENTIFY INTRACELLULAR AMINO-TERMINAL RESIDUES INVOLVED IN LIPID REGULATION OF P2X1 RECEPTORS
por: Allsopp, Rebecca C., et al.
Publicado: (2010)

α/β Hydrolase Domain-containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate
por: Pribasnig, Maria A., et al.
Publicado: (2015)

Imaging cholesterol depletion at the plasma membrane by methyl-β-cyclodextrin
por: Abe, Mitsuhiro, et al.
Publicado: (2021)

Regulation and Essentiality of the StAR-related Lipid Transfer (START) Domain-containing Phospholipid Transfer Protein PFA0210c in Malaria Parasites
por: Hill, Ross J., et al.
Publicado: (2016)

Patatin-like phospholipase domain–containing protein 3 promotes transfers of essential fatty acids from triglycerides to phospholipids in hepatic lipid droplets
por: Mitsche, Matthew A., et al.
Publicado: (2018)

CC-Chemokine Ligand 2 (CCL2) Suppresses High Density Lipoprotein (HDL) Internalization and Cholesterol Efflux via CC-Chemokine Receptor 2 (CCR2) Induction and p42/44 Mitogen-activated Protein Kinase (MAPK) Activation in Human Endothelial Cells
por: Sun, Run-Lu, et al.
Publicado: (2016)

Antioxidant-rich spice added to hamburger meat during cooking results in reduced meat, plasma, and urine malondialdehyde concentrations(1)(2)(3)(4)
por: Li, Zhaoping, et al.
Publicado: (2010)

Low Density Lipoprotein Binds to Proprotein Convertase Subtilisin/Kexin Type-9 (PCSK9) in Human Plasma and Inhibits PCSK9-mediated Low Density Lipoprotein Receptor Degradation
por: Kosenko, Tanja, et al.
Publicado: (2013)

Decrease in Membrane Phospholipid Unsaturation Induces Unfolded Protein Response
por: Ariyama, Hiroyuki, et al.
Publicado: (2010)

High-fat meals rich in EPA plus DHA compared with DHA only have differential effects on postprandial lipemia and plasma 8-isoprostane F(2α) concentrations relative to a control high–oleic acid meal: a randomized controlled trial(1)(2)(3)(4)
por: Purcell, Robert, et al.
Publicado: (2014)

Triglycerides and HDL Cholesterol: Stars or second leads in diabetes?
por: Bitzur, Rafael, et al.
Publicado: (2009)

Relationship between non–high-density lipoprotein cholesterol/apolipoprotein A-I and monocyte/high-density lipoprotein cholesterol ratio and coronary heart disease
por: Li, Ya, et al.
Publicado: (2020)

High-density lipoprotein cholesterol as a predictor of clinical outcomes in patients achieving low-density lipoprotein cholesterol targets with statins after percutaneous coronary intervention
por: Seo, Suk Min, et al.
Publicado: (2011)

Identification of Plant-like Galactolipids in Chromera velia, a Photosynthetic Relative of Malaria Parasites
por: Botté, Cyrille Y., et al.
Publicado: (2011)

Purification, Identification, and Cloning of Lysoplasmalogenase, the Enzyme That Catalyzes Hydrolysis of the Vinyl Ether Bond of Lysoplasmalogen
por: Wu, Lai-Chu, et al.
Publicado: (2011)

A Sequence Variation (I148M) in PNPLA3 Associated with Nonalcoholic Fatty Liver Disease Disrupts Triglyceride Hydrolysis
por: He, Shaoqing, et al.
Publicado: (2010)

Identification and Structure Determination of Novel Anti-inflammatory Mediator Resolvin E3, 17,18-Dihydroxyeicosapentaenoic Acid
por: Isobe, Yosuke, et al.
Publicado: (2012)

Expression and Characterization of a PNPLA3 Protein Isoform (I148M) Associated with Nonalcoholic Fatty Liver Disease
por: Huang, Yongcheng, et al.
Publicado: (2011)

Ceramide Kinase Regulates the Production of Tumor Necrosis Factor α (TNFα) via Inhibition of TNFα-converting Enzyme
por: Lamour, Nadia F., et al.
Publicado: (2011)

Functional and Topological Analysis of Yeast Acyl-CoA:Diacylglycerol Acyltransferase 2, an Endoplasmic Reticulum Enzyme Essential for Triacylglycerol Biosynthesis
por: Liu, Qin, et al.
Publicado: (2011)

Ataxin-1 Poly(Q)-induced Proteotoxic Stress and Apoptosis Are Attenuated in Neural Cells by Docosahexaenoic Acid-derived Neuroprotectin D1
por: Calandria, Jorgelina M., et al.
Publicado: (2012)

Phospholipid-esterified Eicosanoids Are Generated in Agonist-activated Human Platelets and Enhance Tissue Factor-dependent Thrombin Generation
por: Thomas, Christopher P., et al.
Publicado: (2010)

Metabolic and Transcriptional Responses of Glycerolipid Pathways to a Perturbation of Glycerol 3-Phosphate Metabolism in Arabidopsis
por: Shen, Wenyun, et al.
Publicado: (2010)

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages
por: Aflaki, Elma, et al.
Publicado: (2011)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase
por: Chandak, Prakash G., et al.
Publicado: (2010)

Identification of a Mammalian-type Phosphatidylglycerophosphate Phosphatase in the Eubacterium Rhodopirellula baltica
por: Teh, Phildrich G., et al.
Publicado: (2013)

Conformational Plasticity and Ligand Binding of Bacterial Monoacylglycerol Lipase
por: Rengachari, Srinivasan, et al.
Publicado: (2013)

Rapid Production of Platelet-activating Factor Is Induced by Protein Kinase Cα-mediated Phosphorylation of Lysophosphatidylcholine Acyltransferase 2 Protein
por: Morimoto, Ryo, et al.
Publicado: (2014)

Biosynthesis and Translocation of Unsulfated Acyltrehaloses in Mycobacterium tuberculosis
por: Belardinelli, Juan Manuel, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_585pisohtvh3tf009gesrmm9hn