Cargando…

Prevalence of Parasomnia in Autistic Children with Sleep Disorders

The prevalence of sleep related complaints is reported by questionnaire studies to be as high as 83.3% in children with autism spectrum disorders (ASD). Questionnaire studies report the presence of various parasomnia in ASD. However, no polysomnographic study reports non-REM parasomnias and only a s...

Descripción completa

Detalles Bibliográficos
Autores principales: Ming, Xue, Sun, Ye-Ming, Nachajon, Roberto V., Brimacombe, Michael, Walters, Arthur S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676289/
https://www.ncbi.nlm.nih.gov/pubmed/23818789
_version_ 1782272614952075264
author Ming, Xue
Sun, Ye-Ming
Nachajon, Roberto V.
Brimacombe, Michael
Walters, Arthur S.
author_facet Ming, Xue
Sun, Ye-Ming
Nachajon, Roberto V.
Brimacombe, Michael
Walters, Arthur S.
author_sort Ming, Xue
collection PubMed
description The prevalence of sleep related complaints is reported by questionnaire studies to be as high as 83.3% in children with autism spectrum disorders (ASD). Questionnaire studies report the presence of various parasomnia in ASD. However, no polysomnographic study reports non-REM parasomnias and only a single study reports REM related parasomnias in ASD. We investigated the prevalence and characteristics of sleep disorders by polysomnographic study and questionnaires in a cohort of 23 children with ASD and 23 age-matched children of a non-autistic comparison group. The results showed significantly more non-REM parasomnias in 14 children with ASD on polysomnograms (PSG) and 16 ASD children by questionnaire, a finding that was not associated with medication use, other comorbid medical or psychiatric disorders, or sleep disordered breathing. Of the 14 children with ASD who had PSG evidence of parasomnia, 11 of them had a history suggestive of parasomnia by questionnaire. There was a high sensitivity but a low specificity of parasomnia in ASD by questionnaire in predicting the presence of parasomnia in the PSG. Of the parasomnias recorded in the laboratory, 13 ASD children had Disorders of Partial Arousal, consistent with sleep terrors or confusional arousals. Furthermore, multiple episodes of partial arousal occurred in 11 of the 13 ASD children who had PSG evidence of Disorders of Partial Arousal. Of the 11 ASD children with multiple episodes of partial arousal, 6 ASD children had multiple partial arousals during both nights’ PSG study. Sleep architecture was abnormal in children with ASD, characterized by increased spontaneous arousals, prolonged REM latency and reduced REM percentage. These results suggest a high prevalence of parasomnia in this cohort of children with ASD and a careful history intake of symptoms compatible with parasomnia could be prudent to diagnose parasomnia in ASD children when performing a PSG is not possible.
format Online
Article
Text
id pubmed-3676289
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Libertas Academica
record_format MEDLINE/PubMed
spelling pubmed-36762892013-07-01 Prevalence of Parasomnia in Autistic Children with Sleep Disorders Ming, Xue Sun, Ye-Ming Nachajon, Roberto V. Brimacombe, Michael Walters, Arthur S. Clin Med Pediatr Original Research The prevalence of sleep related complaints is reported by questionnaire studies to be as high as 83.3% in children with autism spectrum disorders (ASD). Questionnaire studies report the presence of various parasomnia in ASD. However, no polysomnographic study reports non-REM parasomnias and only a single study reports REM related parasomnias in ASD. We investigated the prevalence and characteristics of sleep disorders by polysomnographic study and questionnaires in a cohort of 23 children with ASD and 23 age-matched children of a non-autistic comparison group. The results showed significantly more non-REM parasomnias in 14 children with ASD on polysomnograms (PSG) and 16 ASD children by questionnaire, a finding that was not associated with medication use, other comorbid medical or psychiatric disorders, or sleep disordered breathing. Of the 14 children with ASD who had PSG evidence of parasomnia, 11 of them had a history suggestive of parasomnia by questionnaire. There was a high sensitivity but a low specificity of parasomnia in ASD by questionnaire in predicting the presence of parasomnia in the PSG. Of the parasomnias recorded in the laboratory, 13 ASD children had Disorders of Partial Arousal, consistent with sleep terrors or confusional arousals. Furthermore, multiple episodes of partial arousal occurred in 11 of the 13 ASD children who had PSG evidence of Disorders of Partial Arousal. Of the 11 ASD children with multiple episodes of partial arousal, 6 ASD children had multiple partial arousals during both nights’ PSG study. Sleep architecture was abnormal in children with ASD, characterized by increased spontaneous arousals, prolonged REM latency and reduced REM percentage. These results suggest a high prevalence of parasomnia in this cohort of children with ASD and a careful history intake of symptoms compatible with parasomnia could be prudent to diagnose parasomnia in ASD children when performing a PSG is not possible. Libertas Academica 2009-01-22 /pmc/articles/PMC3676289/ /pubmed/23818789 Text en © 2009 The authors. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Original Research
Ming, Xue
Sun, Ye-Ming
Nachajon, Roberto V.
Brimacombe, Michael
Walters, Arthur S.
Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title_full Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title_fullStr Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title_full_unstemmed Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title_short Prevalence of Parasomnia in Autistic Children with Sleep Disorders
title_sort prevalence of parasomnia in autistic children with sleep disorders
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676289/
https://www.ncbi.nlm.nih.gov/pubmed/23818789
work_keys_str_mv AT mingxue prevalenceofparasomniainautisticchildrenwithsleepdisorders
AT sunyeming prevalenceofparasomniainautisticchildrenwithsleepdisorders
AT nachajonrobertov prevalenceofparasomniainautisticchildrenwithsleepdisorders
AT brimacombemichael prevalenceofparasomniainautisticchildrenwithsleepdisorders
AT waltersarthurs prevalenceofparasomniainautisticchildrenwithsleepdisorders