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The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

In mice, successful development and reproduction require that all cells, including germ cells, transition from a pluripotent to a differentiated state. This transition is associated with silencing of the pluripotency genes Oct4 and Nanog. Interestingly, these genes are repressed at different develop...

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Detalles Bibliográficos
Autores principales: Okumura, Leah M., Lesch, Bluma J., Page, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676325/
https://www.ncbi.nlm.nih.gov/pubmed/23762465
http://dx.doi.org/10.1371/journal.pone.0066062

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