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A Saccharomyces cerevisiae Assay System to Investigate Ligand/AdipoR1 Interactions That Lead to Cellular Signaling
Adiponectin is a mammalian hormone that exerts anti-diabetic, anti-cancer and cardioprotective effects through interaction with its major ubiquitously expressed plasma membrane localized receptors, AdipoR1 and AdipoR2. Here, we report a Saccharomyces cerevisiae based method for investigating agonist...
Autores principales: | Aouida, Mustapha, Kim, Kangchang, Shaikh, Abdul Rajjak, Pardo, Jose M., Eppinger, Jörg, Yun, Dae-Jin, Bressan, Ray A., Narasimhan, Meena L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676391/ https://www.ncbi.nlm.nih.gov/pubmed/23762377 http://dx.doi.org/10.1371/journal.pone.0065454 |
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