CENP-A confers a reduction in height on octameric nucleosomes

Nucleosomes in which histone H3 is replaced by CENP-A direct kinetochore assembly. CENP-A nucleosomes extracted from human and Drosophila cells have been reported to have reduced heights relative to canonical octameric H3 nucleosomes, suggesting a unique tetrameric, hemisomal composition. We demonst...

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Detalles Bibliográficos
Autores principales: Miell, Matthew D. D., Fuller, Colin J., Guse, Annika, Barysz, Helena M., Downes, Andrew, Owen-Hughes, Tom, Rappsilber, Juri, Straight, Aaron F., Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676451/
https://www.ncbi.nlm.nih.gov/pubmed/23644598
http://dx.doi.org/10.1038/nsmb.2574

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