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“Super p53” Mice Display Retinal Astroglial Changes

Tumour-suppressor genes, such as the p53 gene, produce proteins that inhibit cell division under adverse conditions, as in the case of DNA damage, radiation, hypoxia, or oxidative stress (OS). The p53 gene can arrest proliferation and trigger death by apoptosis subsequent to several factors. In astr...

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Detalles Bibliográficos
Autores principales: Salazar, Juan J., Gallego-Pinazo, Roberto, de Hoz, Rosa, Pinazo-Durán, Maria D., Rojas, Blanca, Ramírez, Ana I., Serrano, Manuel, Ramírez, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676457/
https://www.ncbi.nlm.nih.gov/pubmed/23762373
http://dx.doi.org/10.1371/journal.pone.0065446