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Kif3a Controls Murine Nephron Number Via GLI3 Repressor, Cell Survival, and Gene Expression in a Lineage-Specific Manner
The primary cilium is required during early embryo patterning, epithelial tubulogenesis, and growth factor-dependent signal transduction. The requirement for primary cilia during renal epithelial-mesenchymal tissue interactions that give rise to nephrons is undefined. Here, we used Cre-mediated reco...
Autores principales: | Chi, Lijun, Galtseva, Alevtina, Chen, Lin, Mo, Rong, Hui, Chi-chung, Rosenblum, Norman D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676467/ https://www.ncbi.nlm.nih.gov/pubmed/23762375 http://dx.doi.org/10.1371/journal.pone.0065448 |
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