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Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants
The membrane transport system is built on the proper functioning of the endoplasmic reticulum (ER). The accumulation of unfolded proteins in the ER lumen (ER stress) disrupts ER homeostasis and disturbs the transport system. In response to ER stress, eukaryotic cells activate intracellular signaling...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676789/ https://www.ncbi.nlm.nih.gov/pubmed/23629671 http://dx.doi.org/10.3390/ijms14059396 |
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author | Hayashi, Shimpei Wakasa, Yuhya Takaiwa, Fumio |
author_facet | Hayashi, Shimpei Wakasa, Yuhya Takaiwa, Fumio |
author_sort | Hayashi, Shimpei |
collection | PubMed |
description | The membrane transport system is built on the proper functioning of the endoplasmic reticulum (ER). The accumulation of unfolded proteins in the ER lumen (ER stress) disrupts ER homeostasis and disturbs the transport system. In response to ER stress, eukaryotic cells activate intracellular signaling (named the unfolded protein response, UPR), which contributes to the quality control of secretory proteins. On the other hand, the deleterious effects of UPR on plant health and growth characteristics have frequently been overlooked, due to limited information on this mechanism. However, recent studies have shed light on the molecular mechanism of plant UPR, and a number of its unique characteristics have been elucidated. This study briefly reviews the progress of understanding what is happening in plants under ER stress conditions. |
format | Online Article Text |
id | pubmed-3676789 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-36767892013-07-02 Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants Hayashi, Shimpei Wakasa, Yuhya Takaiwa, Fumio Int J Mol Sci Review The membrane transport system is built on the proper functioning of the endoplasmic reticulum (ER). The accumulation of unfolded proteins in the ER lumen (ER stress) disrupts ER homeostasis and disturbs the transport system. In response to ER stress, eukaryotic cells activate intracellular signaling (named the unfolded protein response, UPR), which contributes to the quality control of secretory proteins. On the other hand, the deleterious effects of UPR on plant health and growth characteristics have frequently been overlooked, due to limited information on this mechanism. However, recent studies have shed light on the molecular mechanism of plant UPR, and a number of its unique characteristics have been elucidated. This study briefly reviews the progress of understanding what is happening in plants under ER stress conditions. Molecular Diversity Preservation International (MDPI) 2013-04-29 /pmc/articles/PMC3676789/ /pubmed/23629671 http://dx.doi.org/10.3390/ijms14059396 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Hayashi, Shimpei Wakasa, Yuhya Takaiwa, Fumio Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title | Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title_full | Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title_fullStr | Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title_full_unstemmed | Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title_short | Recent Advances in Understanding the Control of Secretory Proteins by the Unfolded Protein Response in Plants |
title_sort | recent advances in understanding the control of secretory proteins by the unfolded protein response in plants |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676789/ https://www.ncbi.nlm.nih.gov/pubmed/23629671 http://dx.doi.org/10.3390/ijms14059396 |
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