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Oxidative Stress Mediates the Disruption of Airway Epithelial Tight Junctions through a TRPM2-PLCγ1-PKCα Signaling Pathway

Oxidative stress has been implicated as an important contributing factor in the pathogenesis of several pulmonary inflammatory diseases. Previous studies have indicated a relationship between oxidative stress and the attenuation of epithelial tight junctions (TJs). In Human Bronchial Epithelial-16 c...

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Detalles Bibliográficos
Autores principales: Xu, Rui, Li, Qi, Zhou, Xiang-Dong, Perelman, Juliy M., Kolosov, Victor P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676794/
https://www.ncbi.nlm.nih.gov/pubmed/23629676
http://dx.doi.org/10.3390/ijms14059475