Cargando…

Oxidative Stress Mediates the Disruption of Airway Epithelial Tight Junctions through a TRPM2-PLCγ1-PKCα Signaling Pathway

Oxidative stress has been implicated as an important contributing factor in the pathogenesis of several pulmonary inflammatory diseases. Previous studies have indicated a relationship between oxidative stress and the attenuation of epithelial tight junctions (TJs). In Human Bronchial Epithelial-16 c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Rui, Li, Qi, Zhou, Xiang-Dong, Perelman, Juliy M., Kolosov, Victor P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676794/ https://www.ncbi.nlm.nih.gov/pubmed/23629676 http://dx.doi.org/10.3390/ijms14059475

Ejemplares similares

The Degradation of Airway Epithelial Tight Junctions in Asthma Under High Airway Pressure Is Probably Mediated by Piezo-1
por: Zhou, Jia, et al.
Publicado: (2021)

The degradation of airway tight junction protein under acidic conditions is probably mediated by transient receptor potential vanilloid 1 receptor
por: Xu, Rui, et al.
Publicado: (2013)

Effects of Scutellarin on MUC5AC Mucin Production Induced by Human Neutrophil Elastase or Interleukin 13 on Airway Epithelial Cells
por: Jiang, De-Peng, et al.
Publicado: (2011)

Effect of epithelium ATP release on cyclic pressure-induced airway mucus secretion
por: Tong, Jin, et al.
Publicado: (2014)

Selective regulation of osteoclast adhesion and spreading by PLCγ/PKCα-PKCδ/RhoA-Rac1 signaling
por: Kim, Jin-Man, et al.
Publicado: (2018)

Triiodothyronine Represses MUC5AC Expression by Antagonizing Sp1 Binding to Its Promoter in Human Bronchial Epithelial HBE16 Cells
por: Wang, Xiaolong, et al.
Publicado: (2012)

Tight junction disruption by cadmium in an in vitro human airway tissue model
por: Cao, Xuefei, et al.
Publicado: (2015)

Protein phosphatase 2A associates with and regulates atypical PKC and the epithelial tight junction complex
por: Nunbhakdi-Craig, Viyada, et al.
Publicado: (2002)

Metformin attenuates the effect of Staphylococcus aureus on airway tight junctions by increasing PKCζ‐mediated phosphorylation of occludin
por: Kalsi, Kameljit K., et al.
Publicado: (2018)

Visualisation of Multiple Tight Junctional Complexes in Human Airway Epithelial Cells
por: Buckley, Alysia G., et al.
Publicado: (2018)

Airway tight junctions as targets of viral infections: Tight Junctions and Viral Infections
por: Linfield, Debra T., et al.
Publicado: (2021)

Oncogenic Raf-1 Disrupts Epithelial Tight Junctions via Downregulation of Occludin
por: Li, Danxi, et al.
Publicado: (2000)

German Cockroach Extract Induces Matrix Metalloproteinase-1 Expression, Leading to Tight Junction Disruption in Human Airway Epithelial Cells
por: Lee, Kyung Eun, et al.
Publicado: (2018)

Effects of sevoflurane on tight junction protein expression and PKC-α translocation after pulmonary ischemia–reperfusion injury
por: Chai, Jun, et al.
Publicado: (2015)

Roles and mechanisms of TRPC3 and the PLCγ/PKC/CPI-17 signaling pathway in regulating parturition
por: Chen, Jing, et al.
Publicado: (2018)

Roles and mechanisms of TRPC3 and the PLCγ/PKC/CPI-17 signaling pathway in regulating parturition
por: Chen, Jing, et al.
Publicado: (2018)

Regulation of Tight Junctions in Upper Airway Epithelium
por: Kojima, Takashi, et al.
Publicado: (2013)

Incense smoke-induced oxidative stress disrupts tight junctions and bronchial epithelial barrier integrity and induces airway hyperresponsiveness in mouse lungs
por: Yamamoto, Norio, et al.
Publicado: (2021)

PKCδ Localization at the Membrane Increases Matrix Traction Force Dependent on PLCγ1/EGFR Signaling
por: Jamison, Joshua, et al.
Publicado: (2013)

Amarogentin, a Secoiridoid Glycoside, Abrogates Platelet Activation through PLCγ2-PKC and MAPK Pathways
por: Yen, Ting-Lin, et al.
Publicado: (2014)

Enteropathogenic Escherichia coli (EPEC) Recruitment of PAR Polarity Protein Atypical PKCζ to Pedestals and Cell–Cell Contacts Precedes Disruption of Tight Junctions in Intestinal Epithelial Cells
por: Tapia, Rocio, et al.
Publicado: (2020)

TRPM2 promotes pancreatic cancer by PKC/MAPK pathway
por: Lin, Rui, et al.
Publicado: (2021)

Lipoxin receptor agonist and inhibition of LTA(4) hydrolase prevent tight junction disruption caused by P. aeruginosa filtrate in airway epithelial cells
por: Kalsi, Kameljit K., et al.
Publicado: (2023)

Alveolar epithelial glycocalyx shedding aggravates the epithelial barrier and disrupts epithelial tight junctions in acute respiratory distress syndrome
por: Li, Jun, et al.
Publicado: (2021)

Effect of TRPM8 and TRPA1 Polymorphisms on COPD Predisposition and Lung Function in COPD Patients
por: Naumov, Denis E., et al.
Publicado: (2021)

IL-13 Impairs Tight Junctions in Airway Epithelia
por: Schmidt, Hanna, et al.
Publicado: (2019)

Nasal Epithelial Barrier Integrity and Tight Junctions Disruption in Allergic Rhinitis: Overview and Pathogenic Insights
por: Nur Husna, Siti Muhamad, et al.
Publicado: (2021)

JAM-A and aPKC: A close pair during cell-cell contact maturation and tight junction formation in epithelial cells
por: Ebnet, Klaus
Publicado: (2013)

Transcriptional Regulators of Claudins in Epithelial Tight Junctions
por: Khan, Niamat, et al.
Publicado: (2015)

Implications of AMPK in the Formation of Epithelial Tight Junctions
por: Rowart, Pascal, et al.
Publicado: (2018)

PDGF-BB enhances collagen gel contraction through a PI3K-PLCγ-PKC-cofilin pathway
por: Reyhani, Vahid, et al.
Publicado: (2017)

Licochalcone A Prevents Platelet Activation and Thrombus Formation through the Inhibition of PLCγ2-PKC, Akt, and MAPK Pathways
por: Lien, Li-Ming, et al.
Publicado: (2017)

Esculetin, a Coumarin Derivative, Prevents Thrombosis: Inhibitory Signaling on PLCγ2–PKC–AKT Activation in Human Platelets
por: Hsia, Chih-Wei, et al.
Publicado: (2019)

Tea Polyphenols Protects Tracheal Epithelial Tight Junctions in Lung during Actinobacillus pleuropneumoniae Infection via Suppressing TLR-4/MAPK/PKC-MLCK Signaling
por: Li, Xiaoyue, et al.
Publicado: (2023)

The Na(+), K(+)-ATPase β1 subunit regulates epithelial tight junctions via MRCKα
por: Bai, Haiqing, et al.
Publicado: (2021)

An Atypical PKC Directly Associates and Colocalizes at the Epithelial Tight Junction with ASIP, a Mammalian Homologue of Caenorhabditis elegans Polarity Protein PAR-3
por: Izumi, Yasushi, et al.
Publicado: (1998)

Structural basis for disruption of claudin assembly in tight junctions by an enterotoxin
por: Shinoda, Takehiro, et al.
Publicado: (2016)

Claudin Loss-of-Function Disrupts Tight Junctions and Impairs Amelogenesis
por: Bardet, Claire, et al.
Publicado: (2017)

TNF-α Signals Through PKCζ/NF-κB to Alter the Tight Junction Complex and Increase Retinal Endothelial Cell Permeability
por: Aveleira, Célia A., et al.
Publicado: (2010)

Bile duct epithelial tight junctions and barrier function
por: Rao, R.K., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_8eiio1qe11fkkj5pre4207bn2p