Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi

In the past few years, extracellular vesicles (EVs) from at least eight fungal species were characterized. EV proteome in four fungal species indicated putative biogenesis pathways and suggested interesting similarities with mammalian exosomes. Moreover, as observed for mammalian exosomes, fungal EV...

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Detalles Bibliográficos
Autores principales: Oliveira, Débora L., Rizzo, Juliana, Joffe, Luna S., Godinho, Rodrigo M. C., Rodrigues, Marcio L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676800/
https://www.ncbi.nlm.nih.gov/pubmed/23644887
http://dx.doi.org/10.3390/ijms14059581
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author Oliveira, Débora L.
Rizzo, Juliana
Joffe, Luna S.
Godinho, Rodrigo M. C.
Rodrigues, Marcio L.
author_facet Oliveira, Débora L.
Rizzo, Juliana
Joffe, Luna S.
Godinho, Rodrigo M. C.
Rodrigues, Marcio L.
author_sort Oliveira, Débora L.
collection PubMed
description In the past few years, extracellular vesicles (EVs) from at least eight fungal species were characterized. EV proteome in four fungal species indicated putative biogenesis pathways and suggested interesting similarities with mammalian exosomes. Moreover, as observed for mammalian exosomes, fungal EVs were demonstrated to be immunologically active. Here we review the seminal and most recent findings related to the production of EVs by fungi. Based on the current literature about secretion of fungal molecules and biogenesis of EVs in eukaryotes, we focus our discussion on a list of cellular proteins with the potential to regulate vesicle biogenesis in the fungi.
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spelling pubmed-36768002013-07-02 Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi Oliveira, Débora L. Rizzo, Juliana Joffe, Luna S. Godinho, Rodrigo M. C. Rodrigues, Marcio L. Int J Mol Sci Review In the past few years, extracellular vesicles (EVs) from at least eight fungal species were characterized. EV proteome in four fungal species indicated putative biogenesis pathways and suggested interesting similarities with mammalian exosomes. Moreover, as observed for mammalian exosomes, fungal EVs were demonstrated to be immunologically active. Here we review the seminal and most recent findings related to the production of EVs by fungi. Based on the current literature about secretion of fungal molecules and biogenesis of EVs in eukaryotes, we focus our discussion on a list of cellular proteins with the potential to regulate vesicle biogenesis in the fungi. Molecular Diversity Preservation International (MDPI) 2013-05-02 /pmc/articles/PMC3676800/ /pubmed/23644887 http://dx.doi.org/10.3390/ijms14059581 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Oliveira, Débora L.
Rizzo, Juliana
Joffe, Luna S.
Godinho, Rodrigo M. C.
Rodrigues, Marcio L.
Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title_full Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title_fullStr Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title_full_unstemmed Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title_short Where Do They Come from and Where Do They Go: Candidates for Regulating Extracellular Vesicle Formation in Fungi
title_sort where do they come from and where do they go: candidates for regulating extracellular vesicle formation in fungi
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676800/
https://www.ncbi.nlm.nih.gov/pubmed/23644887
http://dx.doi.org/10.3390/ijms14059581
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