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Melatonin Effects on Hard Tissues: Bone and Tooth
Melatonin is an endogenous hormone rhythmically produced in the pineal gland under the control of the suprachiasmatic nucleus (SCN) and the light/dark cycle. This indole plays an important role in many physiological processes including circadian entrainment, blood pressure regulation, seasonal repro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676828/ https://www.ncbi.nlm.nih.gov/pubmed/23665905 http://dx.doi.org/10.3390/ijms140510063 |
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author | Liu, Jie Huang, Fang He, Hong-Wen |
author_facet | Liu, Jie Huang, Fang He, Hong-Wen |
author_sort | Liu, Jie |
collection | PubMed |
description | Melatonin is an endogenous hormone rhythmically produced in the pineal gland under the control of the suprachiasmatic nucleus (SCN) and the light/dark cycle. This indole plays an important role in many physiological processes including circadian entrainment, blood pressure regulation, seasonal reproduction, ovarian physiology, immune function, etc. Recently, the investigation and applications of melatonin in the hard tissues bone and tooth have received great attention. Melatonin has been investigated relative to bone remolding, osteoporosis, osseointegration of dental implants and dentine formation. In the present review, we discuss the large body of published evidence and review data of melatonin effects on hard tissues, specifically, bone and tooth. |
format | Online Article Text |
id | pubmed-3676828 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Molecular Diversity Preservation International (MDPI) |
record_format | MEDLINE/PubMed |
spelling | pubmed-36768282013-07-02 Melatonin Effects on Hard Tissues: Bone and Tooth Liu, Jie Huang, Fang He, Hong-Wen Int J Mol Sci Review Melatonin is an endogenous hormone rhythmically produced in the pineal gland under the control of the suprachiasmatic nucleus (SCN) and the light/dark cycle. This indole plays an important role in many physiological processes including circadian entrainment, blood pressure regulation, seasonal reproduction, ovarian physiology, immune function, etc. Recently, the investigation and applications of melatonin in the hard tissues bone and tooth have received great attention. Melatonin has been investigated relative to bone remolding, osteoporosis, osseointegration of dental implants and dentine formation. In the present review, we discuss the large body of published evidence and review data of melatonin effects on hard tissues, specifically, bone and tooth. Molecular Diversity Preservation International (MDPI) 2013-05-10 /pmc/articles/PMC3676828/ /pubmed/23665905 http://dx.doi.org/10.3390/ijms140510063 Text en © 2013 by the authors; licensee MDPI, Basel, Switzerland http://creativecommons.org/licenses/by/3.0 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
spellingShingle | Review Liu, Jie Huang, Fang He, Hong-Wen Melatonin Effects on Hard Tissues: Bone and Tooth |
title | Melatonin Effects on Hard Tissues: Bone and Tooth |
title_full | Melatonin Effects on Hard Tissues: Bone and Tooth |
title_fullStr | Melatonin Effects on Hard Tissues: Bone and Tooth |
title_full_unstemmed | Melatonin Effects on Hard Tissues: Bone and Tooth |
title_short | Melatonin Effects on Hard Tissues: Bone and Tooth |
title_sort | melatonin effects on hard tissues: bone and tooth |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676828/ https://www.ncbi.nlm.nih.gov/pubmed/23665905 http://dx.doi.org/10.3390/ijms140510063 |
work_keys_str_mv | AT liujie melatonineffectsonhardtissuesboneandtooth AT huangfang melatonineffectsonhardtissuesboneandtooth AT hehongwen melatonineffectsonhardtissuesboneandtooth |