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Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb

Reconstruction with massive bone allograft and autologous vascularised fibula combines the structural strength of the allograft and the advantages of fibula's intrinsic blood supply. We retrospectively analysed the outcome of twelve patients (4 male, 8 female) who received reconstruction with m...

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Autores principales: Rabitsch, Katharina, Maurer-Ertl, Werner, Pirker-Frühauf, Ulrike, Wibmer, Christine, Leithner, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676952/
https://www.ncbi.nlm.nih.gov/pubmed/23766665
http://dx.doi.org/10.1155/2013/160295
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author Rabitsch, Katharina
Maurer-Ertl, Werner
Pirker-Frühauf, Ulrike
Wibmer, Christine
Leithner, Andreas
author_facet Rabitsch, Katharina
Maurer-Ertl, Werner
Pirker-Frühauf, Ulrike
Wibmer, Christine
Leithner, Andreas
author_sort Rabitsch, Katharina
collection PubMed
description Reconstruction with massive bone allograft and autologous vascularised fibula combines the structural strength of the allograft and the advantages of fibula's intrinsic blood supply. We retrospectively analysed the outcome of twelve patients (4 male, 8 female) who received reconstruction with massive bone allograft and autologous vascularised fibula after tumour resection in lower limb. Mean age was 17.8 years (range 11–31 years), with following primaries: Ewing's sarcoma (n = 6), osteosarcoma (n = 4), liposarcoma grade 2 (n = 1), and adamantinoma (n = 1). Mean followup was 38.7 months (median 25.7 months; range 2–88 months). Seven tumours were located in the femur and five in the tibia. The mean length of bone defect was 18.7 cm (range 15–25 cm). None of the grafts had to be removed, but there occurred four fractures, four nonunions, and two infections. Two patients developed donor side complication, in form of flexion deformity of the big toe. The event-free survival rate was 51% at two-year followup and 39% at three- and five-year followup. As the complications were manageable, and full weight bearing was achieved in all cases, we consider the combination of massive bone allograft and autologous vascularised fibula a stable and durable reconstruction method of the diaphysis of the lower limbs.
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spelling pubmed-36769522013-06-13 Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb Rabitsch, Katharina Maurer-Ertl, Werner Pirker-Frühauf, Ulrike Wibmer, Christine Leithner, Andreas Sarcoma Clinical Study Reconstruction with massive bone allograft and autologous vascularised fibula combines the structural strength of the allograft and the advantages of fibula's intrinsic blood supply. We retrospectively analysed the outcome of twelve patients (4 male, 8 female) who received reconstruction with massive bone allograft and autologous vascularised fibula after tumour resection in lower limb. Mean age was 17.8 years (range 11–31 years), with following primaries: Ewing's sarcoma (n = 6), osteosarcoma (n = 4), liposarcoma grade 2 (n = 1), and adamantinoma (n = 1). Mean followup was 38.7 months (median 25.7 months; range 2–88 months). Seven tumours were located in the femur and five in the tibia. The mean length of bone defect was 18.7 cm (range 15–25 cm). None of the grafts had to be removed, but there occurred four fractures, four nonunions, and two infections. Two patients developed donor side complication, in form of flexion deformity of the big toe. The event-free survival rate was 51% at two-year followup and 39% at three- and five-year followup. As the complications were manageable, and full weight bearing was achieved in all cases, we consider the combination of massive bone allograft and autologous vascularised fibula a stable and durable reconstruction method of the diaphysis of the lower limbs. Hindawi Publishing Corporation 2013 2013-05-23 /pmc/articles/PMC3676952/ /pubmed/23766665 http://dx.doi.org/10.1155/2013/160295 Text en Copyright © 2013 Katharina Rabitsch et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Rabitsch, Katharina
Maurer-Ertl, Werner
Pirker-Frühauf, Ulrike
Wibmer, Christine
Leithner, Andreas
Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title_full Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title_fullStr Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title_full_unstemmed Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title_short Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb
title_sort intercalary reconstructions with vascularised fibula and allograft after tumour resection in the lower limb
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676952/
https://www.ncbi.nlm.nih.gov/pubmed/23766665
http://dx.doi.org/10.1155/2013/160295
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