Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques

Polycystin-1 is a large transmembrane protein, which, when mutated, causes autosomal dominant polycystic kidney disease, one of the most common life-threatening genetic diseases that is a leading cause of kidney failure. The REJ (receptor for egg lelly) module is a major component of PC1 ectodomain...

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Detalles Bibliográficos
Autores principales: Xu, Meixiang, Ma, Liang, Bujalowski, Paul J., Qian, Feng, Sutton, R. Bryan, Oberhauser, Andres F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677617/
https://www.ncbi.nlm.nih.gov/pubmed/23762046
http://dx.doi.org/10.1155/2013/525231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677617/
https://www.ncbi.nlm.nih.gov/pubmed/23762046
http://dx.doi.org/10.1155/2013/525231

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