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Generation of oligodendroglial cells by direct lineage conversion

Transplantation of oligodendrocyte precursor cells (OPCs) is a promising potential therapeutic strategy for diseases affecting myelin. However, the derivation of engraftable OPCs from human pluripotent stem cells has proven difficult and primary OPCs are not readily available. Here we report the gen...

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Detalles Bibliográficos
Autores principales: Yang, Nan, Zuchero, J. Bradley, Ahlenius, Henrik, Marro, Samuele, Ng, Yi Han, Vierbuchen, Thomas, Hawkins, John S., Geissler, Richard, Barres, Ben A., Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677690/
https://www.ncbi.nlm.nih.gov/pubmed/23584610
http://dx.doi.org/10.1038/nbt.2564