Cargando…

Motivational Disturbances and Effects of L-dopa Administration in Neurofibromatosis-1 Model Mice

Children with neurofibromatosis type 1 (NF1) frequently have cognitive and behavioral deficits. Some of these deficits have been successfully modeled in Nf1 genetically-engineered mice that develop optic gliomas (Nf1 OPG mice). In the current study, we show that abnormal motivational influences affe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wozniak, David F., Diggs-Andrews, Kelly A., Conyers, Sara, Yuede, Carla M., Dearborn, Joshua T., Brown, Jacquelyn A., Tokuda, Kazuhiro, Izumi, Yukitoshi, Zorumski, Charles F., Gutmann, David H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677926/ https://www.ncbi.nlm.nih.gov/pubmed/23762458 http://dx.doi.org/10.1371/journal.pone.0066024

Ejemplares similares

GABA and Endocannabinoids Mediate Depotentiation of Schaffer Collateral Synapses Induced by Stimulation of Temperoammonic Inputs
por: Izumi, Yukitoshi, et al.
Publicado: (2016)

Neuregulin and Dopamine D4 Receptors Contribute Independently to Depotentiation of Schaffer Collateral LTP by Temperoammonic Path Stimulation
por: Izumi, Yukitoshi, et al.
Publicado: (2017)

Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule‐associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1
por: Stein, Liana R., et al.
Publicado: (2017)

Experimentally Induced Mammalian Models of Glaucoma
por: Ishikawa, Makoto, et al.
Publicado: (2015)

Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis
por: Izumi, Yukitoshi, et al.
Publicado: (2015)

Metaplastic LTP inhibition after LTD induction in CA1 hippocampal slices involves NMDA Receptor-mediated Neurosteroidogenesis
por: Izumi, Yukitoshi, et al.
Publicado: (2013)

24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure
por: Ishikawa, Makoto, et al.
Publicado: (2016)

The herbicide glyphosate inhibits hippocampal long-term potentiation and learning through activation of pro-inflammatory signaling
por: Izumi, Yukitoshi, et al.
Publicado: (2023)

The herbicide glyphosate inhibits hippocampal long-term potentiation and learning through activation of pro-inflammatory signaling
por: Izumi, Yukitoshi, et al.
Publicado: (2023)

Conditional knockout of UBC13 produces disturbances in gait and spontaneous locomotion and exploration in mice
por: Wozniak, David F., et al.
Publicado: (2019)

Oxysterols Modulate the Acute Effects of Ethanol on Hippocampal N-Methyl-d-Aspartate Receptors, Long-Term Potentiation, and Learning
por: Izumi, Yukitoshi, et al.
Publicado: (2021)

Acrylamide inhibits long-term potentiation and learning involving microglia and pro-inflammatory signaling
por: Izumi, Yukitoshi, et al.
Publicado: (2022)

Neurofibromatosis Type 1 and Chronic Neurological Conditions in the United States: An Administrative Claims Analysis
por: Madubata, Chinwe C., et al.
Publicado: (2014)

Additive neuroprotective effects of 24(S)-hydroxycholesterol and allopregnanolone in an ex vivo rat glaucoma model
por: Ishikawa, Makoto, et al.
Publicado: (2018)

Brain tumors in neurofibromatosis type 1
por: Costa, Amanda De Andrade, et al.
Publicado: (2019)

A Clickable Analogue of Ketamine Retains NMDA Receptor Activity, Psychoactivity, and Accumulates in Neurons
por: Emnett, Christine, et al.
Publicado: (2016)

SSRIs differentially modulate the effects of pro-inflammatory stimulation on hippocampal plasticity and memory via sigma 1 receptors and neurosteroids
por: Izumi, Yukitoshi, et al.
Publicado: (2023)

Putting a stop to nonsense: Revisiting gene correction therapy for neurofibromatosis type 1
por: Gutmann, David H.
Publicado: (2023)

RAS and beyond: the many faces of the neurofibromatosis type 1 protein
por: Anastasaki, Corina, et al.
Publicado: (2022)

Using the Neurofibromatosis Tumor Predisposition Syndromes to Understand Normal Nervous System Development
por: Garcia, Cynthia, et al.
Publicado: (2014)

Neurosteroids as stress modulators and neurotherapeutics: lessons from the retina
por: Izumi, Yukitoshi, et al.
Publicado: (2022)

Striatal mGlu(5)-mediated synaptic plasticity is independently regulated by location-specific receptor pools and divergent signaling pathways
por: Jong, Yuh-Jiin I., et al.
Publicado: (2023)

Neurofibromatosis Type 1-Associated Optic Pathway Gliomas: Current Challenges and Future Prospects
por: Tang, Yunshuo, et al.
Publicado: (2023)

Neurofibromatosis-1 Gene Mutational Profiles Differ Between Syndromic Disease and Sporadic Cancers
por: Bewley, Alice F., et al.
Publicado: (2022)

Updated nomenclature for human and mouse neurofibromatosis type 1 genes
por: Anastasaki, Corina, et al.
Publicado: (2017)

Challenges in Drug Discovery for Neurofibromatosis Type 1-Associated Low-Grade Glioma
por: Ricker, Cora A., et al.
Publicado: (2016)

Effects of CYP46A1 Inhibition on Long-Term-Depression in Hippocampal Slices ex vivo and 24S-Hydroxycholesterol Levels in Mice in vivo
por: Popiolek, Michael, et al.
Publicado: (2020)

The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy
por: Ishikawa, Makoto, et al.
Publicado: (2022)

L-DOPA
por: Hornykiewicz, Oleh
Publicado: (2017)

Predictive Modeling for Clinical Features Associated With Neurofibromatosis Type 1
por: Morris, Stephanie M., et al.
Publicado: (2021)

Chronic Salsolinol Administration Prevents the Behavioral and Neurochemical Effects of l-DOPA in Rats
por: Wąsik, Agnieszka, et al.
Publicado: (2015)

A Conserved Circadian Function for the Neurofibromatosis 1 Gene
por: Bai, Lei, et al.
Publicado: (2018)

Pain symptomology, functional impact, and treatment of people with Neurofibromatosis type 1
por: Buono, Frank D, et al.
Publicado: (2019)

Pharmacokinetics, metabolism and safety of deuterated L‐DOPA (SD‐1077)/carbidopa compared to L‐DOPA/carbidopa following single oral dose administration in healthy subjects
por: Schneider, Frank, et al.
Publicado: (2018)

Familial Lipomas Without Classic Neurofibromatosis-1 Caused by a Missense Germline NF1 Mutation
por: Ramirez, Erika, et al.
Publicado: (2021)

Commentary: Identification of Mutation Regions on NF1 Responsible for High- and Low-Risk Development of Optic Pathway Glioma in Neurofibromatosis Type I
por: Anastasaki, Corina, et al.
Publicado: (2019)

L-Dopa and Behavior
por: Kebabian, John
Publicado: (1974)

Neurofibromatosis-1 regulation of neural stem cell proliferation and multilineage differentiation operates through distinct RAS effector pathways
por: Chen, Yi-Hsien, et al.
Publicado: (2015)

Betalain production is possible in anthocyanin-producing plant species given the presence of DOPA-dioxygenase and L-DOPA
por: Harris, Nilangani N, et al.
Publicado: (2012)

Dopamine Transporter Binding Is Unaffected by L-DOPA Administration in Normal and MPTP-Treated Monkeys
por: Fernagut, Pierre-Olivier, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_22pvadr0pm42jb6i070qv8achv