A case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma

We report on a case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. A 70-year-old man was admitted to our hospital with fatigue, myalgia and an elevated creatine phosphokinase level. He was diagnosed as rhabdomyolysis related to sorafenib treatment for advance...

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Detalles Bibliográficos
Autores principales: Tsuji, Kunihiro, Takemura, Kenichi, Minami, Keisuke, Teramoto, Ryota, Nakashima, Keisuke, Yamada, Shinya, Doyama, Hisashi, Oiwake, Hisanori, Hasatani, Kenkou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Japan 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677972/
https://www.ncbi.nlm.nih.gov/pubmed/23766825
http://dx.doi.org/10.1007/s12328-013-0381-2
Descripción
Sumario:We report on a case of rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. A 70-year-old man was admitted to our hospital with fatigue, myalgia and an elevated creatine phosphokinase level. He was diagnosed as rhabdomyolysis related to sorafenib treatment for advanced hepatocellular carcinoma. After discontinuation of sorafenib, his fatigue and myalgia resolved and his creatine phosphokinase level returned to normal. Rhabdomyolysis related to sorafenib treatment is rare adverse effect. This is the first detailed case report of rhabdomyolysis related to sorafenib treatment.

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