Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

Mutations in the glucocerebrosidase (gba) gene cause Gaucher disease (GD), the most common lysosomal storage disorder, and increase susceptibility to Parkinson’s disease (PD). While the clinical and pathological features of idiopathic PD and PD related to gba (PD-GBA) mutations are very similar, cel...

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Detalles Bibliográficos
Autores principales: Osellame, Laura D., Rahim, Ahad A., Hargreaves, Iain P., Gegg, Matthew E., Richard-Londt, Angela, Brandner, Sebastian, Waddington, Simon N., Schapira, Anthony H.V., Duchen, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678026/
https://www.ncbi.nlm.nih.gov/pubmed/23707074
http://dx.doi.org/10.1016/j.cmet.2013.04.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678026/
https://www.ncbi.nlm.nih.gov/pubmed/23707074
http://dx.doi.org/10.1016/j.cmet.2013.04.014

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