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RRE-deleting self-inactivating and self-activating HIV-1 vectors for improved safety
Retroviruses have been shown to efficiently delete sequences between repeats as a consequence of the template switching ability of the viral reverse transcriptase. To evaluate this approach for deriving safety-modified lentiviral vectors, we created HIV-1 vectors engineered to delete the Rev-respons...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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PeerJ Inc.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678115/ https://www.ncbi.nlm.nih.gov/pubmed/23761857 http://dx.doi.org/10.7717/peerj.84 |