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In silico prediction of a disease-associated STIL mutant and its affect on the recruitment of centromere protein J (CENPJ)
Human STIL (SCL/TAL1 interrupting locus) protein maintains centriole stability and spindle pole localisation. It helps in recruitment of CENPJ (Centromere protein J)/CPAP (centrosomal P4.1-associated protein) and other centrosomal proteins. Mutations in STIL protein are reported in several disorders...
Autores principales: | Kumar, Ambuj, Rajendran, Vidya, Sethumadhavan, Rao, Purohit, Rituraj |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678130/ https://www.ncbi.nlm.nih.gov/pubmed/23772360 http://dx.doi.org/10.1016/j.fob.2012.09.003 |
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