Acute Liver Failure Associated with Propylthiouracil in a Pregnant 26-Year-Old Woman

It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of pregnancy. She was successfully treated without l...

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Detalles Bibliográficos
Autores principales: Miyamura, Tatsuo, Kanda, Tatsuo, Minemura, Shoko, Nakamura, Masato, Nakamoto, Shingo, Jiang, Xia, Wu, Shuang, Yasui, Shin, Arai, Makoto, Yokosuka, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2013
Materias:
Published online: May, 2013
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678146/
https://www.ncbi.nlm.nih.gov/pubmed/23798915
http://dx.doi.org/10.1159/000351877
Descripción
Sumario:It seems appropriate to use propylthiouracil to treat maternal hyperthyroidism during the first trimester of pregnancy. We present the case of a 26-year-old woman with acute liver failure associated with propylthiouracil during the first trimester of pregnancy. She was successfully treated without liver transplantation. Attention should be paid to the possible occurrence of propylthiouracil-induced hepatotoxicity even during the first trimester of pregnancy.

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