Liprin-α2 promotes the presynaptic recruitment and turnover of RIM1/CASK to facilitate synaptic transmission

The presynaptic active zone mediates synaptic vesicle exocytosis, and modulation of its molecular composition is important for many types of synaptic plasticity. Here, we identify synaptic scaffold protein liprin-α2 as a key organizer in this process. We show that liprin-α2 levels were regulated by...

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Detalles Bibliográficos
Autores principales: Spangler, Samantha A., Schmitz, Sabine K., Kevenaar, Josta T., de Graaff, Esther, de Wit, Heidi, Demmers, Jeroen, Toonen, Ruud F., Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2013
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678157/
https://www.ncbi.nlm.nih.gov/pubmed/23751498
http://dx.doi.org/10.1083/jcb.201301011

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