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A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress

Hemodynamic forces regulate embryonic organ development, hematopoiesis, vascular remodeling, and atherogenesis. The mechanosensory stimulus of blood flow initiates a complex network of intracellular pathways, including activation of Rac1 GTPase, establishment of endothelial cell (EC) polarity, and r...

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Detalles Bibliográficos
Autores principales:	Liu, Yunhao, Collins, Caitlin, Kiosses, William B., Murray, Ann M., Joshi, Monika, Shepherd, Tyson R., Fuentes, Ernesto J., Tzima, Ellie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678169/ https://www.ncbi.nlm.nih.gov/pubmed/23733346 http://dx.doi.org/10.1083/jcb.201207115

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