A Literature Review on the Efficacy and Safety of Botulinum Toxin: An Injection in Post-Stroke Spasticity

BACKGROUND: A variety of techniques for the management of spasticity have been suggested, including positioning, cryotherapy, splinting and casting, biofeedback, electrical stimulation, and medical management by pharmacological agents, Botulinum toxin A (BTA) is now the pharmacological treatment of...

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Detalles Bibliográficos
Autores principales: Ghasemi, Majid, Salari, Mehri, Khorvash, Fariborz, Shaygannejad, Vahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678211/
https://www.ncbi.nlm.nih.gov/pubmed/23776717
Descripción
Sumario:BACKGROUND: A variety of techniques for the management of spasticity have been suggested, including positioning, cryotherapy, splinting and casting, biofeedback, electrical stimulation, and medical management by pharmacological agents, Botulinum toxin A (BTA) is now the pharmacological treatment of choice in focal spasticity. BTA by blocking acetylcholine release at neuromuscular junctions accounts for its therapeutic action to relieve spasticity. METHODS: A computerized search of Pub Med was carried out to find the latest result about efficacy of BTA in management of post stroke spasticity. RESULT: Among 84 articles were found, frothy of them included in this review and divided to lower and upper extremity. CONCLUSIONS: BTA is a treatment choice in reducing tone and managing post stroke spasticity .

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