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The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes
BACKGROUND: Diabetes is one of the most common chronic diseases in which antioxidant capacity changes. Omega-3 fatty acids have extensive biological effects including their advantage on lipoprotein metabolism, platelet function, cytokine production, clotting, fibrinolysis, and inflammatory factors....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678224/ https://www.ncbi.nlm.nih.gov/pubmed/23776730 |
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author | Hajianfar, Hossein Paknahad, Zamzam Bahonar, Ahmad |
author_facet | Hajianfar, Hossein Paknahad, Zamzam Bahonar, Ahmad |
author_sort | Hajianfar, Hossein |
collection | PubMed |
description | BACKGROUND: Diabetes is one of the most common chronic diseases in which antioxidant capacity changes. Omega-3 fatty acids have extensive biological effects including their advantage on lipoprotein metabolism, platelet function, cytokine production, clotting, fibrinolysis, and inflammatory factors. This study aimed to investigate the effect of omega-3 fatty acid supplements on antioxidant capacity in patients with type 2 diabetes. METHODS: This clinical trial enrolled 71 women with type 2 diabetes in two case (treated with omega-3 capsules) and control (treated with placebo) groups. In the first stage, participants filled out a demographics questionnaire including age, height, weight, waist circumference, and hip circumference.Their blood sample was taken to evaluate glycosylated hemoglobin and antioxidant capacity. Then the case group received intervention for 8 weeks and weight, waist circumference, and hip circumference were measured and a blood sample was taken again. The data were analyzed using SPSS 18 software. RESULTS: The mean difference of antioxidant capacity before and after intervention was significant (P < 0.001). Antioxidant capacity increased in the case group and reduced in the control group. CONCLUSIONS: With regard to the results of the present study, patients with type 2 diabetes increase their antioxidant capacity, enhance their antioxidant defense system, and probably prevent diabetes complications and related disease progress by taking omega-3 supplements. |
format | Online Article Text |
id | pubmed-3678224 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-36782242013-06-17 The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes Hajianfar, Hossein Paknahad, Zamzam Bahonar, Ahmad Int J Prev Med Original Article BACKGROUND: Diabetes is one of the most common chronic diseases in which antioxidant capacity changes. Omega-3 fatty acids have extensive biological effects including their advantage on lipoprotein metabolism, platelet function, cytokine production, clotting, fibrinolysis, and inflammatory factors. This study aimed to investigate the effect of omega-3 fatty acid supplements on antioxidant capacity in patients with type 2 diabetes. METHODS: This clinical trial enrolled 71 women with type 2 diabetes in two case (treated with omega-3 capsules) and control (treated with placebo) groups. In the first stage, participants filled out a demographics questionnaire including age, height, weight, waist circumference, and hip circumference.Their blood sample was taken to evaluate glycosylated hemoglobin and antioxidant capacity. Then the case group received intervention for 8 weeks and weight, waist circumference, and hip circumference were measured and a blood sample was taken again. The data were analyzed using SPSS 18 software. RESULTS: The mean difference of antioxidant capacity before and after intervention was significant (P < 0.001). Antioxidant capacity increased in the case group and reduced in the control group. CONCLUSIONS: With regard to the results of the present study, patients with type 2 diabetes increase their antioxidant capacity, enhance their antioxidant defense system, and probably prevent diabetes complications and related disease progress by taking omega-3 supplements. Medknow Publications & Media Pvt Ltd 2013-05 /pmc/articles/PMC3678224/ /pubmed/23776730 Text en Copyright: © International Journal of Preventive Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Hajianfar, Hossein Paknahad, Zamzam Bahonar, Ahmad The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title | The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title_full | The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title_fullStr | The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title_full_unstemmed | The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title_short | The Effect of Omega-3 Supplements on Antioxidant Capacity in Patients with Type 2 Diabetes |
title_sort | effect of omega-3 supplements on antioxidant capacity in patients with type 2 diabetes |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678224/ https://www.ncbi.nlm.nih.gov/pubmed/23776730 |
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