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OptiMAS: A Decision Support Tool for Marker-Assisted Assembly of Diverse Alleles

Current advances in plant genotyping lead to major progress in the knowledge of genetic architecture of traits of interest. It is increasingly important to develop decision support tools to help breeders and geneticists to conduct marker-assisted selection methods to assemble favorable alleles that...

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Detalles Bibliográficos
Autores principales: Valente, Fabio, Gauthier, Franck, Bardol, Nicolas, Blanc, Guylaine, Joets, Johann, Charcosset, Alain, Moreau, Laurence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678297/
https://www.ncbi.nlm.nih.gov/pubmed/23576670
http://dx.doi.org/10.1093/jhered/est020
Descripción
Sumario:Current advances in plant genotyping lead to major progress in the knowledge of genetic architecture of traits of interest. It is increasingly important to develop decision support tools to help breeders and geneticists to conduct marker-assisted selection methods to assemble favorable alleles that are discovered. Algorithms have been implemented, within an interactive graphical interface, to 1) trace parental alleles throughout generations, 2) propose strategies to select the best plants based on estimated molecular scores, and 3) efficiently intermate them depending on the expected value of their progenies. With the possibility to consider a multi-allelic context, OptiMAS opens new prospects to assemble favorable alleles issued from diverse parents and further accelerate genetic gain.