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Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension
The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. T...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678444/ https://www.ncbi.nlm.nih.gov/pubmed/23781269 http://dx.doi.org/10.1155/2013/808971 |
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author | Chen, Hongyan Dai, Jianping Zhang, Xiaozhe Wang, Kai Huang, Shuhua Cao, Qingtian Wang, Hong Liang, Yuhong Shi, Chuanying Li, Mengyuan Ha, Tingting Ai, Lin Li, Shaowu Ma, Jun Wei, Wenjuan You, Youbo Liu, Zhenyu Tian, Jie Bai, Lijun |
author_facet | Chen, Hongyan Dai, Jianping Zhang, Xiaozhe Wang, Kai Huang, Shuhua Cao, Qingtian Wang, Hong Liang, Yuhong Shi, Chuanying Li, Mengyuan Ha, Tingting Ai, Lin Li, Shaowu Ma, Jun Wei, Wenjuan You, Youbo Liu, Zhenyu Tian, Jie Bai, Lijun |
author_sort | Chen, Hongyan |
collection | PubMed |
description | The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P = 0.005) decreased and vitality (P = 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem. |
format | Online Article Text |
id | pubmed-3678444 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-36784442013-06-18 Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension Chen, Hongyan Dai, Jianping Zhang, Xiaozhe Wang, Kai Huang, Shuhua Cao, Qingtian Wang, Hong Liang, Yuhong Shi, Chuanying Li, Mengyuan Ha, Tingting Ai, Lin Li, Shaowu Ma, Jun Wei, Wenjuan You, Youbo Liu, Zhenyu Tian, Jie Bai, Lijun Evid Based Complement Alternat Med Research Article The present study attempted to explore modulated hypothalamus-seeded resting brain network underlying the cardiovascular system in primary hypertensive patients after short-term acupuncture treatment. Thirty right-handed patients (14 male) were divided randomly into acupuncture and control groups. The acupuncture group received a continuous five-day acupuncture treatment and undertook three resting-state fMRI scans and 24-hour ambulatory blood pressure monitoring (ABPM) as well as SF-36 questionnaires before, after, and one month after acupuncture treatment. The control group undertook fMRI scans and 24-hour ABPM. For verum acupuncture, average blood pressure (BP) and heart rate (HR) decreased after treatment but showed no statistical differences. There were no significant differences in BP and HR between the acupuncture and control groups. Notably, SF-36 indicated that bodily pain (P = 0.005) decreased and vitality (P = 0.036) increased after acupuncture compared to the baseline. The hypothalamus-related brain network showed increased functional connectivity with the medulla, brainstem, cerebellum, limbic system, thalamus, and frontal lobes. In conclusion, short-term acupuncture did not decrease BP significantly but appeared to improve body pain and vitality. Acupuncture may regulate the cardiovascular system through a complicated brain network from the cortical level, the hypothalamus, and the brainstem. Hindawi Publishing Corporation 2013 2013-05-27 /pmc/articles/PMC3678444/ /pubmed/23781269 http://dx.doi.org/10.1155/2013/808971 Text en Copyright © 2013 Hongyan Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Chen, Hongyan Dai, Jianping Zhang, Xiaozhe Wang, Kai Huang, Shuhua Cao, Qingtian Wang, Hong Liang, Yuhong Shi, Chuanying Li, Mengyuan Ha, Tingting Ai, Lin Li, Shaowu Ma, Jun Wei, Wenjuan You, Youbo Liu, Zhenyu Tian, Jie Bai, Lijun Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title | Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title_full | Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title_fullStr | Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title_full_unstemmed | Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title_short | Hypothalamus-Related Resting Brain Network Underlying Short-Term Acupuncture Treatment in Primary Hypertension |
title_sort | hypothalamus-related resting brain network underlying short-term acupuncture treatment in primary hypertension |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678444/ https://www.ncbi.nlm.nih.gov/pubmed/23781269 http://dx.doi.org/10.1155/2013/808971 |
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