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The Haptoglobin-CD163-Heme Oxygenase-1 Pathway for Hemoglobin Scavenging

The haptoglobin- (Hp-) CD163-heme oxygenase-1 (HO-1) pathway is an efficient captor-receptor-enzyme system to circumvent the hemoglobin (Hb)/heme-induced toxicity during physiological and pathological hemolyses. In this pathway, Hb tightly binds to Hp leading to CD163-mediated uptake of the complex...

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Detalles Bibliográficos
Autores principales:	Thomsen, Jens Haugbølle, Etzerodt, Anders, Svendsen, Pia, Moestrup, Søren K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678498/ https://www.ncbi.nlm.nih.gov/pubmed/23781295 http://dx.doi.org/10.1155/2013/523652

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