Transcription factor–mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells

Cell-based therapies for myelin disorders, such as multiple sclerosis and leukodystrophies, require technologies to generate functional oligodendrocyte progenitor cells. Here we describe direct conversion of mouse embryonic and lung fibroblasts to “induced” oligodendrocyte progenitor cells (iOPCs) u...

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Detalles Bibliográficos
Autores principales: Najm, Fadi J., Lager, Angela M., Zaremba, Anita, Wyatt, Krysta, Caprariello, Andrew V., Factor, Daniel C., Karl, Robert T., Maeda, Tadao, Miller, Robert H., Tesar, Paul J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678540/
https://www.ncbi.nlm.nih.gov/pubmed/23584611
http://dx.doi.org/10.1038/nbt.2561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678540/
https://www.ncbi.nlm.nih.gov/pubmed/23584611
http://dx.doi.org/10.1038/nbt.2561

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