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The conjugation of nonsteroidal anti-inflammatory drugs (NSAID) to small peptides for generating multifunctional supramolecular nanofibers/hydrogels

Here we report supramolecular hydrogelators made of nonsteroidal anti-inflammatory drugs (NSAID) and small peptides. The covalent linkage of Phe–Phe and NSAIDs results in conjugates that self-assemble in water to form molecular nanofibers as the matrices of hydrogels. When the NSAID is naproxen (1),...

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Detalles Bibliográficos
Autores principales: Li, Jiayang, Kuang, Yi, Shi, Junfeng, Gao, Yuan, Zhou, Jie, Xu, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678635/
https://www.ncbi.nlm.nih.gov/pubmed/23766806
http://dx.doi.org/10.3762/bjoc.9.104