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Formal synthesis of (−)-agelastatin A: an iron(II)-mediated cyclization strategy

An iron(II)-mediated aminohalogenation of a cyclopentenyl N-tosyloxycarbamate provided new access to the key intermediate for the synthesis of (−)-agelastatin A (AA, 1), a potent antiproliferative alkaloid. The present synthetic endeavour offered an insight into the mechanism underlying the iron(II)...

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Detalles Bibliográficos
Autores principales:	Shigeoka, Daisuke, Kamon, Takuma, Yoshimitsu, Takehiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2013
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678661/ https://www.ncbi.nlm.nih.gov/pubmed/23766801 http://dx.doi.org/10.3762/bjoc.9.99

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