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Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature
Neuroendocrine tumors (NETs) frequently metastasize to the liver, but it is rare to find them there as primary tumors. Isolated polycystic liver disease (PCLD) is a rare autosomal dominant disease. There is no known association between polycystic liver disease and neuroendocrine or other tumors. We...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678662/ https://www.ncbi.nlm.nih.gov/pubmed/23761831 http://dx.doi.org/10.3892/ol.2013.1233 |
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author | KOUTSAMPASOPOULOS, KONSTANTINOS ANTONIADOU, ELISAVET ZOUTIS, STAVROS IACOVIDIS, GRIGORIOS BUROVA, OLGA TAPLIDIS, ANTONIOS |
author_facet | KOUTSAMPASOPOULOS, KONSTANTINOS ANTONIADOU, ELISAVET ZOUTIS, STAVROS IACOVIDIS, GRIGORIOS BUROVA, OLGA TAPLIDIS, ANTONIOS |
author_sort | KOUTSAMPASOPOULOS, KONSTANTINOS |
collection | PubMed |
description | Neuroendocrine tumors (NETs) frequently metastasize to the liver, but it is rare to find them there as primary tumors. Isolated polycystic liver disease (PCLD) is a rare autosomal dominant disease. There is no known association between polycystic liver disease and neuroendocrine or other tumors. We report a case of a 64-year-old female with a past medical history of isolated PCLD who presented with increasing abdominal pain over a two-week period. Our patient underwent open surgical biopsy one month after presentation. The histological examination and immunohistochemical findings suggested an intermediate grade neuroendocrine tumor. A 24-h delayed whole-body scintigraphy technique was utilized for the identification and localization of neuroendocrine tumors via the administration of In-111-labeled OctreoScan; however, no extrahepatic accumulation was observed. No previous studies in the literature describe a patient with PCLD and a primary or metastatic neuroendocrine tumor of the liver. |
format | Online Article Text |
id | pubmed-3678662 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-36786622013-06-11 Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature KOUTSAMPASOPOULOS, KONSTANTINOS ANTONIADOU, ELISAVET ZOUTIS, STAVROS IACOVIDIS, GRIGORIOS BUROVA, OLGA TAPLIDIS, ANTONIOS Oncol Lett Articles Neuroendocrine tumors (NETs) frequently metastasize to the liver, but it is rare to find them there as primary tumors. Isolated polycystic liver disease (PCLD) is a rare autosomal dominant disease. There is no known association between polycystic liver disease and neuroendocrine or other tumors. We report a case of a 64-year-old female with a past medical history of isolated PCLD who presented with increasing abdominal pain over a two-week period. Our patient underwent open surgical biopsy one month after presentation. The histological examination and immunohistochemical findings suggested an intermediate grade neuroendocrine tumor. A 24-h delayed whole-body scintigraphy technique was utilized for the identification and localization of neuroendocrine tumors via the administration of In-111-labeled OctreoScan; however, no extrahepatic accumulation was observed. No previous studies in the literature describe a patient with PCLD and a primary or metastatic neuroendocrine tumor of the liver. D.A. Spandidos 2013-05 2013-03-06 /pmc/articles/PMC3678662/ /pubmed/23761831 http://dx.doi.org/10.3892/ol.2013.1233 Text en Copyright © 2013, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Articles KOUTSAMPASOPOULOS, KONSTANTINOS ANTONIADOU, ELISAVET ZOUTIS, STAVROS IACOVIDIS, GRIGORIOS BUROVA, OLGA TAPLIDIS, ANTONIOS Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title | Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title_full | Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title_fullStr | Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title_full_unstemmed | Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title_short | Neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: A case report and review of the literature |
title_sort | neuroendocrine tumor in the liver of a patient with isolated polycystic liver disease: a case report and review of the literature |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678662/ https://www.ncbi.nlm.nih.gov/pubmed/23761831 http://dx.doi.org/10.3892/ol.2013.1233 |
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