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Pomegranate for Your Cardiovascular Health

Pomegranate is a source of some very potent antioxidants (tannins, anthocyanins) which are considered to be also potent anti-atherogenic agents. The combination of the above unique various types of pomegranate polyphenols provides a much wider spectrum of action against several types of free radical...

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Autores principales: Aviram, Michael, Rosenblat, Mira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rambam Health Care Campus 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678830/
https://www.ncbi.nlm.nih.gov/pubmed/23908863
http://dx.doi.org/10.5041/RMMJ.10113
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author Aviram, Michael
Rosenblat, Mira
author_facet Aviram, Michael
Rosenblat, Mira
author_sort Aviram, Michael
collection PubMed
description Pomegranate is a source of some very potent antioxidants (tannins, anthocyanins) which are considered to be also potent anti-atherogenic agents. The combination of the above unique various types of pomegranate polyphenols provides a much wider spectrum of action against several types of free radicals. Indeed, pomegranate is superior in comparison to other antioxidants in protecting low-density lipoprotein (LDL, “the bad cholesterol”) and high-density lipoprotein (HDL, “the good cholesterol”) from oxidation, and as a result it attenuates atherosclerosis development and its consequent cardiovascular events. Pomegranate antioxidants are not free, but are attached to the pomegranate sugars, and hence were shown to be beneficial even in diabetic patients. Furthermore, pomegranate antioxidants are unique in their ability to increase the activity of the HDL-associated paraoxonase 1 (PON1), which breaks down harmful oxidized lipids in lipoproteins, in macrophages, and in atherosclerotic plaques. Finally, unique pomegranate antioxidants beneficially decrease blood pressure. All the above beneficial characteristics make the pomegranate a uniquely healthy fruit.
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spelling pubmed-36788302013-08-01 Pomegranate for Your Cardiovascular Health Aviram, Michael Rosenblat, Mira Rambam Maimonides Med J Clinical Implications of Basic Research Pomegranate is a source of some very potent antioxidants (tannins, anthocyanins) which are considered to be also potent anti-atherogenic agents. The combination of the above unique various types of pomegranate polyphenols provides a much wider spectrum of action against several types of free radicals. Indeed, pomegranate is superior in comparison to other antioxidants in protecting low-density lipoprotein (LDL, “the bad cholesterol”) and high-density lipoprotein (HDL, “the good cholesterol”) from oxidation, and as a result it attenuates atherosclerosis development and its consequent cardiovascular events. Pomegranate antioxidants are not free, but are attached to the pomegranate sugars, and hence were shown to be beneficial even in diabetic patients. Furthermore, pomegranate antioxidants are unique in their ability to increase the activity of the HDL-associated paraoxonase 1 (PON1), which breaks down harmful oxidized lipids in lipoproteins, in macrophages, and in atherosclerotic plaques. Finally, unique pomegranate antioxidants beneficially decrease blood pressure. All the above beneficial characteristics make the pomegranate a uniquely healthy fruit. Rambam Health Care Campus 2013-04-30 /pmc/articles/PMC3678830/ /pubmed/23908863 http://dx.doi.org/10.5041/RMMJ.10113 Text en Copyright: © 2013 Aviram and Rosenblat. This is an open-access article. All its content, except where otherwise noted, is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Implications of Basic Research
Aviram, Michael
Rosenblat, Mira
Pomegranate for Your Cardiovascular Health
title Pomegranate for Your Cardiovascular Health
title_full Pomegranate for Your Cardiovascular Health
title_fullStr Pomegranate for Your Cardiovascular Health
title_full_unstemmed Pomegranate for Your Cardiovascular Health
title_short Pomegranate for Your Cardiovascular Health
title_sort pomegranate for your cardiovascular health
topic Clinical Implications of Basic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678830/
https://www.ncbi.nlm.nih.gov/pubmed/23908863
http://dx.doi.org/10.5041/RMMJ.10113
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