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Synaptic Changes in the Dentate Gyrus of APP/PS1 Transgenic Mice Revealed by Electron Microscopy

Numerous studies have reported widespread synaptic dysfunction or loss in early stages of both Alzheimer disease (AD) patients and animal models; it is widely accepted that synapse loss is the major structural correlate of cognitive dysfunction. Elucidation of the changes that may affect synapses is...

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Detalles Bibliográficos
Autores principales:	Alonso-Nanclares, Lidia, Merino-Serrais, Paula, Gonzalez, Santiago, DeFelipe, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association of Neuropathologists 2013
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3678882/ https://www.ncbi.nlm.nih.gov/pubmed/23584198 http://dx.doi.org/10.1097/NEN.0b013e31828d41ec

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