A Mechanistic Study on the Destabilization of Whole Inactivated Influenza Virus Vaccine in Gastric Environment

Oral immunization using whole inactivated influenza virus vaccine promises an efficient vaccination strategy. While oral vaccination was hampered by harsh gastric environment, a systematic understanding about vaccine destabilization mechanisms was not performed. Here, we investigated the separate an...

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Detalles Bibliográficos
Autores principales: Choi, Hyo-Jick, Ebersbacher, Charles F., Kim, Min-Chul, Kang, Sang-Moo, Montemagno, Carlo D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679046/
https://www.ncbi.nlm.nih.gov/pubmed/23776657
http://dx.doi.org/10.1371/journal.pone.0066316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679046/
https://www.ncbi.nlm.nih.gov/pubmed/23776657
http://dx.doi.org/10.1371/journal.pone.0066316

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