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Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling

PURPOSE: To identify preoperative markers on spectral domain optical coherence tomography (SD-OCT) for residual inner limiting membrane (ILM) in epiretinal membrane (ERM) peeling. METHODS: In this retrospective case series the preoperative SD-OCTs from 119 eyes of 119 consecutive patients who underw...

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Autores principales: Seidel, Gerald, Weger, Martin, Stadlmüller, Lisa, Pichler, Tamara, Haas, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679048/
https://www.ncbi.nlm.nih.gov/pubmed/23776634
http://dx.doi.org/10.1371/journal.pone.0066217
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author Seidel, Gerald
Weger, Martin
Stadlmüller, Lisa
Pichler, Tamara
Haas, Anton
author_facet Seidel, Gerald
Weger, Martin
Stadlmüller, Lisa
Pichler, Tamara
Haas, Anton
author_sort Seidel, Gerald
collection PubMed
description PURPOSE: To identify preoperative markers on spectral domain optical coherence tomography (SD-OCT) for residual inner limiting membrane (ILM) in epiretinal membrane (ERM) peeling. METHODS: In this retrospective case series the preoperative SD-OCTs from 119 eyes of 119 consecutive patients who underwent surgery for idiopathic ERM by a single surgeon were evaluated for markers predisposing for ILM persistence after ERM removal. ILM persistence was determined via intraoperative indocyanine green staining. The main outcome measures were correlation of central foveal thickness (CFT), ERM thickness, extent of elevated ERM and retinal folding, intraretinal cysts, and discontinuation of the ERM, with ILM persistence after ERM peeling. RESULTS: The persistence of the ILM was found in 50.4% (n = 60). After Bonferroni correction for multiple testing, a greater extent of elevated ERM and thicker ERMs were associated with persistence of the ILM (p<0.005). The other parameters showed no statistically significant correlations with the persistence of the ILM (p≥0.005). CONCLUSION: Residual ILM can be found in nearly half of the eyes after ERM peeling. A loose connection between the ERM and the retinal surface predisposes for ILM persistence. Preoperative SD-OCT is helpful in identifying risk markers for the persistence of the ILM in ERM surgery.
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spelling pubmed-36790482013-06-17 Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling Seidel, Gerald Weger, Martin Stadlmüller, Lisa Pichler, Tamara Haas, Anton PLoS One Research Article PURPOSE: To identify preoperative markers on spectral domain optical coherence tomography (SD-OCT) for residual inner limiting membrane (ILM) in epiretinal membrane (ERM) peeling. METHODS: In this retrospective case series the preoperative SD-OCTs from 119 eyes of 119 consecutive patients who underwent surgery for idiopathic ERM by a single surgeon were evaluated for markers predisposing for ILM persistence after ERM removal. ILM persistence was determined via intraoperative indocyanine green staining. The main outcome measures were correlation of central foveal thickness (CFT), ERM thickness, extent of elevated ERM and retinal folding, intraretinal cysts, and discontinuation of the ERM, with ILM persistence after ERM peeling. RESULTS: The persistence of the ILM was found in 50.4% (n = 60). After Bonferroni correction for multiple testing, a greater extent of elevated ERM and thicker ERMs were associated with persistence of the ILM (p<0.005). The other parameters showed no statistically significant correlations with the persistence of the ILM (p≥0.005). CONCLUSION: Residual ILM can be found in nearly half of the eyes after ERM peeling. A loose connection between the ERM and the retinal surface predisposes for ILM persistence. Preoperative SD-OCT is helpful in identifying risk markers for the persistence of the ILM in ERM surgery. Public Library of Science 2013-06-11 /pmc/articles/PMC3679048/ /pubmed/23776634 http://dx.doi.org/10.1371/journal.pone.0066217 Text en © 2013 Seidel et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Seidel, Gerald
Weger, Martin
Stadlmüller, Lisa
Pichler, Tamara
Haas, Anton
Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title_full Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title_fullStr Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title_full_unstemmed Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title_short Association of Preoperative Optical Coherence Tomography Markers with Residual Inner Limiting Membrane in Epiretinal Membrane Peeling
title_sort association of preoperative optical coherence tomography markers with residual inner limiting membrane in epiretinal membrane peeling
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679048/
https://www.ncbi.nlm.nih.gov/pubmed/23776634
http://dx.doi.org/10.1371/journal.pone.0066217
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