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DAP12 Overexpression Induces Osteopenia and Impaired Early Hematopoiesis

ITAM-bearing transmembrane signaling adaptors such as DAP12 and FcRγ are important players in bone homeostasis, but their precise role and functions are still unknown. It has been shown that osteoclast differentiation results from the integration of the RANK and of the DAP12 and FcRγ signaling pathw...

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Detalles Bibliográficos
Autores principales: Despars, Geneviève, Pandruvada, Subramanya N. M., Anginot, Adrienne, Domenget, Chantal, Jurdic, Pierre, Mazzorana, Marlène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679081/
https://www.ncbi.nlm.nih.gov/pubmed/23776468
http://dx.doi.org/10.1371/journal.pone.0065297