DC260126: A Small-Molecule Antagonist of GPR40 that Protects against Pancreatic β-Cells Dysfunction in db/db Mice

G protein-coupled receptor 40 (GPR40) mediates both acute and chronic effects of free fatty acids (FFAs) on insulin secretion. However, it remains controversial whether inhibition of GPR40 would be beneficial in prevention of type 2 diabetes. This study is designed to evaluate the potential effects...

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Detalles Bibliográficos
Autores principales: Sun, Peng, Wang, Ting, Zhou, Yuren, Liu, Hong, Jiang, Hualiang, Zhu, Weiliang, Wang, Heyao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679087/
https://www.ncbi.nlm.nih.gov/pubmed/23776696
http://dx.doi.org/10.1371/journal.pone.0066744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679087/
https://www.ncbi.nlm.nih.gov/pubmed/23776696
http://dx.doi.org/10.1371/journal.pone.0066744

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