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Proteolytic cleavage and truncation of NDRG1 in human prostate cancer cells, but not normal prostate epithelial cells

NDRG1 (N-myc downstream regulated gene-1) is a metastasis suppressor that is down-regulated in prostate cancer. NDRG1 phosphorylation is associated with inhibition of metastasis and Western blots indicate two bands at ~41 and ~46 kDa. Previous investigations by others suggest the higher band is due...

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Detalles Bibliográficos
Autores principales:	Ghalayini, Mohammad K., Dong, Qihan, Richardson, Des R., Assinder, Stephen J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2013
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679596/ https://www.ncbi.nlm.nih.gov/pubmed/23634903 http://dx.doi.org/10.1042/BSR20130042

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