No evidence for the development of acute analgesic tolerance during and hyperalgesia after prolonged remifentanil administration in mice

BACKGROUND: Acute opioid tolerance (AOT) and opioid-induced hyperalgesia (OIH) are undesirable effects of opioids that have been reported in both animals and humans. However, the development of AOT and OIH in cases of potent, short-acting μ-opioid receptor agonist remifentanil administration remains...

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Detalles Bibliográficos
Autores principales: Ishii, Hideaki, Petrenko, Andrey B, Kohno, Tatsuro, Baba, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679751/
https://www.ncbi.nlm.nih.gov/pubmed/23497285
http://dx.doi.org/10.1186/1744-8069-9-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679751/
https://www.ncbi.nlm.nih.gov/pubmed/23497285
http://dx.doi.org/10.1186/1744-8069-9-11

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