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Comparative analysis of 4C-Seq data generated from enzyme-based and sonication-based methods
BACKGROUND: Circular chromosome conformation capture, when coupled with next-generation sequencing (4C-Seq), can be used to identify genome-wide interaction of a given locus (a “bait” sequence) with all of its interacting partners. Conventional 4C approaches used restriction enzyme digestion to frag...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679908/ https://www.ncbi.nlm.nih.gov/pubmed/23705979 http://dx.doi.org/10.1186/1471-2164-14-345 |