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A Poisson hierarchical modelling approach to detecting copy number variation in sequence coverage data
BACKGROUND: The advent of next generation sequencing technology has accelerated efforts to map and catalogue copy number variation (CNV) in genomes of important micro-organisms for public health. A typical analysis of the sequence data involves mapping reads onto a reference genome, calculating the...
Autores principales: | Sepúlveda, Nuno, Campino, Susana G, Assefa, Samuel A, Sutherland, Colin J, Pain5, Arnab, Clark, Taane G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679970/ https://www.ncbi.nlm.nih.gov/pubmed/23442253 http://dx.doi.org/10.1186/1471-2164-14-128 |
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