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Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes

BACKGROUND: The use of potentially inappropriate medications (PIM) among the elderly is a serious public health problem because it is intrinsically linked to increased morbidity and mortality, causing high costs to public health systems. This study’s objective was to verify the prevalence of and the...

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Autores principales: Vieira de Lima, Thaís Jaqueline, Garbin, Cléa Adas Saliba, Garbin, Artênio José Ísper, Sumida, Dóris Hissako, Saliba, Orlando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679980/
https://www.ncbi.nlm.nih.gov/pubmed/23718678
http://dx.doi.org/10.1186/1471-2318-13-52
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author Vieira de Lima, Thaís Jaqueline
Garbin, Cléa Adas Saliba
Garbin, Artênio José Ísper
Sumida, Dóris Hissako
Saliba, Orlando
author_facet Vieira de Lima, Thaís Jaqueline
Garbin, Cléa Adas Saliba
Garbin, Artênio José Ísper
Sumida, Dóris Hissako
Saliba, Orlando
author_sort Vieira de Lima, Thaís Jaqueline
collection PubMed
description BACKGROUND: The use of potentially inappropriate medications (PIM) among the elderly is a serious public health problem because it is intrinsically linked to increased morbidity and mortality, causing high costs to public health systems. This study’s objective was to verify the prevalence of and the factors associated with the use of PIMs by elderly Brazilians in institutional settings. METHODS: We performed a transversal study, by consulting the case files of elderly people living in Long Term Care for the Elderly (LTC) in towns in the State of São Paulo, Brazil, as well as structured interviews with the nurses responsible for them. We identified PIMs using the list of recently updated Beers criteria developed by a group of specialists from the American Geriatrics Society (AGS), who reviewed the criteria based on studies with high scientific evidence levels. We defined the factors studied to evaluate the association with PIM use prior to the statistical analyses, which were the chi-square test and multiple logistic regression. RESULTS: Among the elderly who used drugs daily, 82.6% were taking at least one PIM, with antipsychotics (26.5%) and analgesics (15.1%) being the most commonly used. Out of all the medications used, 32.4% were PIMs, with 29.7% of these being PIMs that the elderly should avoid independent of their condition, 1.1% being inappropriate medication for older adults with certain illnesses or syndromes, and 1.6% being medications that older adults should use with caution. In the multivariate analysis, the factors associated with PIM use were: polypharmacy (p = 0.0187), cerebrovascular disease (p = 0.0036), psychiatric disorders (p < 0.0001) and dependency (p = 0.0404). CONCLUSIONS: The results of this study showed a high prevalence of PIM use in institutionalized elderly Brazilian patients. and the associated factors were polypharmacy, psychiatric disorders, cerebrovascular diseases and dependency.
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spelling pubmed-36799802013-06-13 Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes Vieira de Lima, Thaís Jaqueline Garbin, Cléa Adas Saliba Garbin, Artênio José Ísper Sumida, Dóris Hissako Saliba, Orlando BMC Geriatr Research Article BACKGROUND: The use of potentially inappropriate medications (PIM) among the elderly is a serious public health problem because it is intrinsically linked to increased morbidity and mortality, causing high costs to public health systems. This study’s objective was to verify the prevalence of and the factors associated with the use of PIMs by elderly Brazilians in institutional settings. METHODS: We performed a transversal study, by consulting the case files of elderly people living in Long Term Care for the Elderly (LTC) in towns in the State of São Paulo, Brazil, as well as structured interviews with the nurses responsible for them. We identified PIMs using the list of recently updated Beers criteria developed by a group of specialists from the American Geriatrics Society (AGS), who reviewed the criteria based on studies with high scientific evidence levels. We defined the factors studied to evaluate the association with PIM use prior to the statistical analyses, which were the chi-square test and multiple logistic regression. RESULTS: Among the elderly who used drugs daily, 82.6% were taking at least one PIM, with antipsychotics (26.5%) and analgesics (15.1%) being the most commonly used. Out of all the medications used, 32.4% were PIMs, with 29.7% of these being PIMs that the elderly should avoid independent of their condition, 1.1% being inappropriate medication for older adults with certain illnesses or syndromes, and 1.6% being medications that older adults should use with caution. In the multivariate analysis, the factors associated with PIM use were: polypharmacy (p = 0.0187), cerebrovascular disease (p = 0.0036), psychiatric disorders (p < 0.0001) and dependency (p = 0.0404). CONCLUSIONS: The results of this study showed a high prevalence of PIM use in institutionalized elderly Brazilian patients. and the associated factors were polypharmacy, psychiatric disorders, cerebrovascular diseases and dependency. BioMed Central 2013-05-30 /pmc/articles/PMC3679980/ /pubmed/23718678 http://dx.doi.org/10.1186/1471-2318-13-52 Text en Copyright © 2013 Lima et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Vieira de Lima, Thaís Jaqueline
Garbin, Cléa Adas Saliba
Garbin, Artênio José Ísper
Sumida, Dóris Hissako
Saliba, Orlando
Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title_full Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title_fullStr Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title_full_unstemmed Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title_short Potentially inappropriate medications used by the elderly: prevalence and risk factors in Brazilian care homes
title_sort potentially inappropriate medications used by the elderly: prevalence and risk factors in brazilian care homes
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679980/
https://www.ncbi.nlm.nih.gov/pubmed/23718678
http://dx.doi.org/10.1186/1471-2318-13-52
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