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The neonatal CNS is not conducive for encephalitogenic Th1 T cells and B cells during experimental autoimmune encephalomyelitis
Multiple sclerosis (MS) is thought to be a CD4(+) T cell mediated autoimmune demyelinating disease of the central nervous system (CNS) that is rarely diagnosed during infancy. Cellular and molecular mechanisms that confer disease resistance in this age group are unknown. We tested the hypothesis tha...
Autores principales: | Cravens, Petra D, Kieseier, Bernd C, Hussain, Rehana, Herndon, Emily, Arellano, Benjamine, Ben, Li-Hong, Timmons, Brenda C, Castro-Rojas, Cyd, Hartung, Hans-Peter, Hemmer, Bernhard, Weber, Martin S, Zamvil, Scott S, Stüve, Olaf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679999/ https://www.ncbi.nlm.nih.gov/pubmed/23705890 http://dx.doi.org/10.1186/1742-2094-10-67 |
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