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Interferon-α sensitizes HBx-expressing hepatocarcinoma cells to chemotherapeutic drugs through inhibition of HBx-mediated NF-κB activation

BACKGROUND: Hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC) is characterized by high chemotherapy resistance; however, the underlying mechanism has not been fully clarified. In addition, HBx protein has been reported to play a key role in virus-mediated hepatocarcinogenesis. Theref...

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Detalles Bibliográficos
Autores principales:	Liu, Yanning, Lou, Guohua, Wu, Wei, Shi, Yu, Zheng, Min, Chen, Zhi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680016/ https://www.ncbi.nlm.nih.gov/pubmed/23718853 http://dx.doi.org/10.1186/1743-422X-10-168

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