Hypervariable antigen genes in malaria have ancient roots

BACKGROUND: The var genes of the human malaria parasite Plasmodium falciparum are highly polymorphic loci coding for the erythrocyte membrane proteins 1 (PfEMP1), which are responsible for the cytoaherence of P. falciparum infected red blood cells to the human vasculature. Cytoadhesion, coupled with...

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Detalles Bibliográficos
Autores principales: Zilversmit, Martine M, Chase, Ella K, Chen, Donald S, Awadalla, Philip, Day, Karen P, McVean, Gil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680017/
https://www.ncbi.nlm.nih.gov/pubmed/23725540
http://dx.doi.org/10.1186/1471-2148-13-110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680017/
https://www.ncbi.nlm.nih.gov/pubmed/23725540
http://dx.doi.org/10.1186/1471-2148-13-110

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