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Association of genes of protease-antiprotease balance pathway to lung function and emphysema subtypes

BACKGROUND: The imbalance between proteases and antiproteases has been proposed to participate to the pathogenesis of chronic obstructive pulmonary disease (COPD) and emphysema. Gene level variation in different metalloproteinases, metalloproteinase inhibitors, and cytokines affecting them may contr...

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Detalles Bibliográficos
Autores principales:	Kukkonen, Mari K, Tiili, Emmi, Vehmas, Tapio, Oksa, Panu, Piirilä, Päivi, Hirvonen, Ari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680142/ https://www.ncbi.nlm.nih.gov/pubmed/23734748 http://dx.doi.org/10.1186/1471-2466-13-36

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