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Regulation of DNA transposition by CpG methylation and chromatin structure in human cells

BACKGROUND: The activity of transposable elements can be regulated by different means. DNA CpG methylation is known to decrease or inhibit transpositional activity of diverse transposons. However, very surprisingly, it was previously shown that CpG methylation of the Sleeping Beauty (SB) transposon...

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Detalles Bibliográficos
Autores principales: Jursch, Tobias, Miskey, Csaba, Izsvák, Zsuzsanna, Ivics, Zoltán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680223/
https://www.ncbi.nlm.nih.gov/pubmed/23676100
http://dx.doi.org/10.1186/1759-8753-4-15

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