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Temporal and spatial requirements of Smoothened in ventral midbrain neuronal development
BACKGROUND: Several studies have indicated that Sonic hedgehog (Shh) regulates the expansion of dopaminergic (DA) progenitors and the subsequent generation of mature DA neurons. This prevailing view has been based primarily on in vitro culture results, and the exact in vivo function of Shh signaling...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680293/ https://www.ncbi.nlm.nih.gov/pubmed/23618354 http://dx.doi.org/10.1186/1749-8104-8-8 |